Feeds:
Posts
Comments

Posts Tagged ‘insulin resistance’

Earlier this year another victim of this stuck-music condition, which is often called “earworms,” contacted me in desperation. Her husband suffers earworms so bad he often bangs his head against the wall in an effort to quiet them. Or maybe it’s an attempt to bash them out of his head. In any case, my heart broke to hear about how terribly they both were suffering because of this maddening phenomenon.

I pulled out my old research and the stories I’ve collected from victims over the years. My intention is to document the phenomenon and then try again to find researchers with the interest, skills and capabilities to take all this accumulated information and test the chemical/hormonal hypothesis, or at least take the research in more helpful (for us) directions.

In an effort to describe in words what the experience is like for those of us being driven mad by the earworms, I recalled a recent vacation roadtrip with my husband in which we listened to several music CDs in the car and at the cabin in the mountains. I won’t even mention the artist whose double-CD ended up playing in my head for weeks (and now months) after the trip.  But since then, my earworms have grown much worse.

If you’ve read my posts, you know that for the past 10 years or so I had effectively silenced my earworms by balancing my hormones (through the use of bio-identical hormones) and taking a supplement that reduces cortisol. But, as the story of our roadtrip reveals, the earworms are coming back, and they are disruptive at times.

Curiously, I’ve also been having issues with my hormones, specifically my estrogen patches, for the past year or more, since my doctor switched me to the generic patches. Whereas the original patches used to last 4 to 6 days, the generic patch wore off within 2 days, sometimes less. Last fall, the doctor approved my use of the brand-name patches again, but even those don’t last as long as they used to.

The hormone problems and the earworms’ return are almost certainly connected.

My current goal is to find and contact researchers who are already interested in this phenomenon. There are quite a few more studies and researchers now than there were some 10 years ago when I began my quest. Unfortunately, none of them seem to be looking at chemical causes. However, I am encouraged because several of the researchers seem to be serious about discovering the cause(s) of the earworms and treatments/techniques to get rid of them. Several papers mention that the authors are looking for testable hypotheses that might shed more light on this phenomenon. Well, I just happen to have one.

So I am about to contact as many researchers as I can find. If any of them agree to study the chemistry of earworms, I would like to connect them with those of you who have this condition…with your permission, of course.

Meanwhile, I wanted to get the word out to all of you and ask you to please send me your earworm stories, if you haven’t already.  If you wish to be anonymous, just let me know and I will pass along only your story, without your name or contact information.

You can contact me by email at hormonebook@yahoo.com  Share whatever information you think is relevant.

Please answer the following specific questions if you can:

  1. When did the earworms start? How old were you and what were the circumstances in your life and health at the time they first started?
  2. What exposure have you had to brain-altering drugs (anti-depressants, anti-psychotics, anti-seizure meds) before or during the earworms? Did any drugs stop the earworms?
  3. What effect does stress or emotional excitement (good or bad) have on the earworms?
  4. How “loud” or disruptive are the earworms?
  5. What, if anything, affects the earworms, brings them on/makes them “louder” or makes them fade away? (Actions/”tricks,” foods, supplements, etc.)
  6. What sex are you?
  7. Do you take any hormones? If so specify.
  8. Are you thirsty a lot?
  9. Do you have diabetes?
  10. How long have you had the earworms?
  11. If they come and go, please describe the length of the episodes and describe any circumstances that seem associated with the earworms being on versus off.
  12. Can you control the earworms (turn them on/off)? If yes, please describe how.
  13. Would you be willing to communicate with researchers about your earworm experiences?
  14. Would you be willing to participate in lab studies (brain scans, blood/saliva tests, etc.) investigating earworms?

Thank you all for following my blog and for sharing your experiences. I will do whatever I can to find relief for us all!

As always, wishing you peace and quiet.

Pat

 

Read Full Post »

Here I am, still fighting the ebb and flow of this recent recurrence of the stuck music (auditory memory loops/AMLs). (I now suspect I have gotten a bad box of estrogen patches, and will see if this resolves when I start on the new box.) Meanwhile, I decided to try searching OCD (obsessive compulsive disorder) sites for new perspectives.

Do I really have OCD?

The first thing I looked at was a self test for OCD.  I failed miserably (or should I say “happily”). Classic OCD is associated with repetitive rituals (like locking the door the “right” number of times, or incessant hand washing) and a lot of dark thoughts and fears. The TV character Adrian Monk had OCD (among other issues). His list of fears/phobias began with “Germs, needles, milk, death….”  Yes, in that order.

I apparently don’t have OCD in the sense these tests define it. I have no rituals, no dark thoughts, and no phobias/fears other than: (a) spiders (since childhood), (b) 4-leaf clovers (long story), and, most important, (c) the fear of having songs stuck in my head again and not being able to enjoy…or even truly live life.

OCD – Melanie’s Article

Despite my apparent lack of OCD symptoms,  I searched for OCD and hormones and came up with a fabulous article from Melanie Gladney’s HubPage.  http://melaniegladney.hubpages.com/hub/OCD-Glucose-Metabolism-and-Food-Allergies This focuses on classical OCD, but offers suggestions that may work for some of us as well. It is certainly worth a shot.

OCD and Hormones

In this article, she discusses the same hormonal influences I’ve identified, but she adds important dimensions to the discussion, including information about key brain chemicals that the sex hormones trigger.

She emphasizes the role of progesterone in calming anxieties. Just keep in mind that, for me at least, there is a very narrow sweet spot for progesterone levels: if I get too much (relative to estrogen), it actually brings on the stuck music.  But as we know, we all have different body chemistries and reactions, so keep progesterone in your toolbox and use it carefully, like everything else.

OCD and Blood Sugar, Insulin Resistance and Cortisol 

More important, Melanie covers in great detail the role of blood sugar/metabolism and  food allergies as they may relate to OCD. Her suggestions about diet require more self discipline than I am easily capable of, but they have worked for her OCD, so please check them out and see if her suggestions might work for you.

Remember that high cortisol can not only trigger or exacerbate the AMLs, it can induce insulin resistance (which Melanie talks about in easy-to-understand detail). So maybe it’s not the cortisol directly that affects our AMLs after all, but the insulin/metabolic conditions that result from that cortisol overload. Maybe regulating blood sugar and/or insulin is, in fact, the answer…or at least part of it.

Is it that simple? Probably not.

From a logical standpoint, it seems that if blood sugar, food allergies, and insulin resistance were truly at the root of this (in my case, at least), then I should not have been able to get rid of the AMLs when I implemented my current hormone regimen, because I did not change my diet. The only things I changed were: (1) I took cortisol suppressing supplements, and (2) I created a mini hormone cycle with a surge of estrogen 24 hours before I took my progesterone.

This same kind of reasoning told me that it’s not just cortisol that triggers the AMLs, because I have been way more stressed in my younger life (i.e., had tons of adrenalin and cortisol surging through my body) and yet I did not get songs stuck in my head.  This only started when my sex hormones went south at menopause…and it only went away again when I mimicked a youthful hormone cycle.

Then again, the most obvious difference between the identical twin boys who shared most everything except the AMLs was that the one who had the AMLs turned out to have a then-undiagnosed metabolic disorder involving insulin resistance. The mom obtained the diagnosis after reading about the cortisol/metabolic connection to AMLs here and taking her son in for relevant tests. So, clearly the AMLs and metabolic dysfunction are closely linked.

Visit Melanie

The bottom line is that Melanie and I seem to be running down the same rabbit hole, chasing the same two suspects–sex hormone imbalances and dysfunctional metabolic/adrenal processes–from slightly different perspectives. So I encourage you to check out her hub. (You can read the articles but may have to join HubPages.com to comment.) And write to her if you think she can help. She seems to be very generous in responding.

And if any of you try her suggestions, please keep us posted on the results, whether positive, negative or neutral.

Wishing you a blissfully quiet day.

Pat

BTW, Last night I attended a lecture by a neuroscientist, and he has promised to put me in touch with someone he thinks might be able to help us or at least can point us to someone else who might. Cross your fingers…

Read Full Post »